Quintanilla-Martinez Leticia …
,
de Jong Daphne,
de Mascarel Antoine,
Hsi Eric D.,
Kluin Philip,
Natkunam Yaso,
Parrens Marie,
Pileri Stefano, Ott German » «
However, the precise mechanism by which genistein suppresses tumorigenesis remain unclear.
Disturbance of miRNA expression and function leads to deregulation of basic cellular processes leading to tumorigenesis.
Dietary components potentially influence fundamental cellular processes involved in carcinogenesis, including apoptosis, cell-cycle control, angiogenesis, inflammation and DNA repair.
Examination of tumor-specific miRNA expression profiles has revealed widespread dysregulation of these molecules in diverse cancers.
At the end of the experiment the tumors were freeze-clamped and stored at −80°C.
Tumor necrosis was quantified as the % area of tumor replaced by necrosis, as identified by light microscopy [].
These in vitro findings were confirmed in vivo in tumors grown subcutaneously as xenografts in mice in all three groups.
21 tumors were evaluated after H+E staining, and each exhibited a high Fuhrman's tumor grade of either 3 or 4, with the majority of tumors demonstrating sarcomatoid dedifferentiation.
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such as "what causes B".
Then, add additional terms, such as "mice", and dates when you filter the results.
Authors and journals should be entered into their own search boxes.
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This tab displays documents containing relationships that match your query.
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This tab displays documents simply containing your search terms,
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To remove any filter, click its .
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Filter documents to those that contain the additional term anywhere within the relevant text
including the title, abstract, body (for full-text), and MeSH terms.
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be also be listed in separate sections.
If your query contains the term "what" (for example, "what controls cell cycle"), the first set of
terms listed are specifically from the portion of the relationship that might contain the "what".
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may be of interest.
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Since Quertle searches for Relationships,
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View all Power Terms.
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Relationships are conceptual facts based on the context and implication of the text.
A document may have more than one relationship relevant to your search.
Click on "Expand All Relationships" to view more relationships.
Keyword Results, in contrast, are independent of context and
simply have your search terms anywhere within the document.
Results Order
Results are initially ordered by relevance to your search.
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will be sorted based on their expected publication date.
Easy to Use Filters
Several types of filters, such as Published Within (date)
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Key Concepts
In the Filters section, use the automatically extracted Key Concepts
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General Concepts, as well as action words can also be used for filtering.
Click on the desired term to limit the relationships shown to those containing
the selected concept.
Highlighting
Terms (and their synonyms) used in your query will be highlighted.
You have the option to turn highlighting off.
Power Terms™
Use any of the following Power Terms in your query to represent an entire class of related concepts.
Click on a term to add it to the current query (or type them directly).
Power Terms can be combined in a single query.
The most common Power Terms are shown below; for more, see the
full list of Power Terms.
Sample queries for several fields are shown. Click the desired query to execute any of the samples.
Note that queries are focused on Relationships, leaving modifier terms to be applied as filters.
Molecular Biology Examples
p53 Bax - looking for relationships
between these proteins
p53 $PositiveActions Foxp3 - looking specifically
for papers that have
the concept "p53 has a positive effect on Foxp3" - not simply papers that include the terms
cell cycle - looking for information
about this process
.
